Phenomics Australia supports bushfire research, recovery & resilience

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Phenomics Australia provides expertise and customised model systems necessary for preclinical biomedical research on the effects of bushfires on human health.

Australia’s National Research Infrastructure supports bushfire research, recovery, and resilience understanding human health impacts, providing access to genomic, and bioinformatics resources, modelling, and predicting fires, monitoring ecosystem recovery, and more. Download infographic here.

Phenomics Australia NCRIS infrastructure is used in providing expertise and customised model systems necessary for pre-clinical biomedical research on the effects of bushfires on human health. Including, but not limited to, air pollution exposure during pregnancy, and respiratory and ocular diseases.

Exposure of trophoblast cells to fine particulate matter air pollution leads to growth inhibition, inflammation and ER stress.

Ambient air pollution is considered a major environmental health threat to pregnant women. Our previous work has shown an association between exposure to airborne particulate matter (PM) and an increased risk of developing pre-eclampsia. Read more here.

Air pollution exposure during pregnancy

IFITM3 and type I interferons are important for the control of influenza A virus replication in murine macrophages.

In humans, influenza A virus (IAV) infection is predominantly restricted to the respiratory tract (Taubenberger and Morens, 2008), where infection of airway epithelial cells results in productive virus replication and release of newly-synthesised virions. Read more here.

Respiratory disease

Transient receptor potential cation channel subfamily V member 1 expressing corneal sensory neurons can be subdivided into at least three subpopulations.

Sensory neurons play an important role in protection of the cornea and in maintaining corneal epithelial integrity. Read more here.

Ocular disease

Topographical and Morphological Differences of Corneal Dendritic Cells during Steady State and Inflammation.

Clinical imaging of the corneal microstructure by IVCM is an important diagnostic tool for a range of ocular conditions including dry eye disease1-3, diabetic complications4–6 and keratitis. Read more here.

Cornea Inflammation

As identified in the National Research Infrastructure Roadmap 2021, in coming years, Australia will face unprecedented challenges due to changes to our climate and environment. World‑class climate and environmental science is required to inform successful adaptation approaches that will help protect communities, infrastructure, industries, environments and biodiversity.

These investments will deliver comprehensive, world-leading environmental monitoring that, among others, will provide improved management of pollutant sources and responses to bushfires and dust storms. A step-change in this capability will help identify regions and communities at greatest risk from climate threats and enable adaptation.

Phenomics Australia Feedback Form

Phenomics Australia (formerly the Australian Phenomics Network, APN) offers consolidated infrastructure and expertise supporting genomic medicine and biomedical research from discovery through into early clinical development and evaluation.

Phenomics Australia is a founding capability enabled by the National Collaborative Research Infrastructure Strategy (NCRIS). We would love to hear from you!

Please feel free to provide any ideas or general comments you might have so that we can further improve how Phenomics Australia can support you.

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