Disease Models Data Resources

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Wondering where to find disease models data? Below is a list of databases and resources you can start with.

Mouse Genome Informatics (MGI) is the international database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data to facilitate the study of human health and disease.

Latest: MGI has integrated the latest C57BL/6J assembly, GRCm39. This includes annotations from NCBI and Ensembl, and updated coordinates for genome features, transcription start sites, and gene traps. SNP coordinates in MGI were not updated to GRCm39 for this release but will be in a future release.

MGI now loads vertebrate orthology data based on the “stringent” set of homology class data from the Alliance of Genome Resources. These data include human, rat, and zebrafish homologs.

The Multiple Genome Viewer (MGV) allows you to browse and compare multiple related genomes, download corresponding sequence regions, display lists of genes, and other functions.

Latest: The MGV has been rewritten to be species agnostic and now includes human, rat, and 4 other model organism reference genomes, as well as the C57BL/6J reference genome (both Build 38 and 39) and 18 other mouse inbred strains. The MGV allows you to explore and compare chromosomal regions between multiple selected species and mouse strains, and to view orthology and inferred paralogy relationships across genomes.

Alliance of Genome Resources: A consortium of 6 model organism databases (MODs) and the Gene Ontology (GO) Consortium whose goal is to provide an integrated view of their data to all biologists, clinicians, and other interested parties.

Latest: The Alliance Community Forum is released. The Forum permits discussions across six model organism communities—flies, mice, yeast, rats, worms, and zebrafish.

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