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Round Lead applicant Affiliation Project title Phenomics Australia node ( Capability provider) DOI
2025-26 Round 2 Miss Ava Owen Murdoch Children's Research Institute Generating a model of variations in female reproductive tract development using a new stem cell reporter line Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI) https://doi.org/10.82509/p4dg-6s42
2025-26 Round 2 Dr Declan Turner Murdoch Children’s Research Institute Developing a human iPSC-derived alveolar coculture platform to model respiratory infection and regeneration Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI) https://doi.org/10.82509/tpwr-xd91
2025-26 Round 2 Prof Gemma Kelly Walter and Eliza Hall Institute of Medical Research Identifying which processes activated by p53 are critical to prevent tumour development to supportthe design of novel cancer therapies Melbourne Advanced Gene Editing Centre (ONJCRI) https://doi.org/10.82509/t5na-pp22
2025-26 Round 2 Dr James McKenna Algorae Sciences Validating the generalizability of artificial intelligence for in silico drug combination prediction Victorian Centre for Functional Genomics (Peter Mac) https://doi.org/10.82509/zb4b-z588
2025-26 Round 2 Dr Jenny Fung University of Queensland CRISPR-Engineered Motor Neuron Disease Cell Models to Enable Target Validation and Accelerate Therapeutic Translation Monash Genome Modification Platform (Monash) https://doi.org/10.82509/j230-aq79
2025-26 Round 2 Dr Kayla Wilson University of Melbourne Targeting Cholesin to Control Viral Immunity Melbourne Advanced Gene Editing Centre (ONJCRI) https://doi.org/10.82509/k9b3-5d27
2025-26 Round 2 Dr Lara Graves Sydney Children’s Hospitals Network Generation of Humanised CYP21A2 Mouse Models to Enable Translational Genome Editing Therapies for Congenital Adrenal Hyperplasia Monash Genome Modification Platform (Monash) https://doi.org/10.82509/wq77-9y82
2025-26 Round 2 Dr Laura Croft Queensland University of Technology Patient-Derived Cortical Organoids to Decipher Disease Mechanisms and Therapeutic Response in SLC6A1-Related NDD Australian Organoid Facility (UQ),StemCore https://doi.org/10.82509/gwzw-ct60
2025-26 Round 2 Dr Madeleine Hardy Australian National University Understanding the genetic basis of Syntelencephaly Genome Targeting Facility (ANU) https://doi.org/10.82509/g39d-8w93
2025-26 Round 2 Dr Nathalie Saurat Monash University Transcriptomic and phenotypic screening of aged human microtissues to advance Alzheimer's disease therapeutics Victorian Centre for Functional Genomics (Peter Mac),Monash Proteomics & Metabolomics Platform https://doi.org/10.82509/9pwg-6v56
2025-26 Round 2 Dr Peter Johnson Australian National University Developing a Scalable Hydrogel Discovery Platform for 3D Cancer Modelling ANU Centre for Therapeutic Discovery (ANU) https://doi.org/10.82509/5dkz-5d35
2025-26 Round 2 Dr Richard Burke Monash University In vivo functional characterisation of candidate pathogenic variants in ubiquitin proteasome components Australian Transgenic Drosophila Facility (Peter Mac) https://doi.org/10.82509/v601-kj52
2025-26 Round 2 Dr Yi Tian Ting Monash University Scalable Allogeneic Tregs Platform for autoimmune diseases Stem Cell Production Facility (VCCRI) https://doi.org/10.82509/hcb0-6002
25_26_Round 1 Dr Géza Berecki Florey Institute of Neuroscience and Mental Health Developing an inducible mouse model of neonatal encephalopathy for preclinical evaluation of sodium channel modulators Monash Genome Modification Platform (Monash) https://doi.org/10.82509/0xjh-9034
25_26_Round 1 Dr Jessica Neil University of Melbourne Development of a high-throughput lung epithelial cell screening platform for discovery of broadly-acting antivirals against coronaviruses Victorian Centre for Functional Genomics (PeterMac) https://doi.org/10.82509/bd3x-ap91
25_26_Round 1 Dr Kevin Watt Murdoch Children’s Research Institute Generation of a human stem cell model to screen for efficacy and potency of novel regenerative small molecules Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI) https://doi.org/10.82509/wrk9-xb77
25_26_Round 1 Dr Laura Ellett The Florey Institute of Neuroscience and Mental Health Generating a murine model of genetic prion disease relevant to Australian mutation carriers Monash Genome Modification Platform (Monash) https://doi.org/10.82509/amdr-k705
25_26_Round 1 Prof. Oliver Rackham The Kids Research Institute Australia New preclinical models of mitochondrial disease Monash Genome Modification Platform (Monash) https://doi.org/10.82509/gjzk-wk86
25_26_Round 1 Dr Ryan Leung Murdoch Children's Research Institute Investigating the potential of differentiation therapy for paediatric diffuse hemispheric glioma Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI)andVictorian Centre for Functional Genomics (PeterMac) https://doi.org/10.82509/z11c-d329
25_26_Round 1 Dr Thanh Nha Uyen Le Hudson Institute of Medical Research A multi-omics strategy to reveal hidden genetic drivers in undiagnosed gonadal dysgenesis Phenomics Australia node: Monash Genome Modification PlatformBioplatforms Australia nodes: Australian Genome Research Facility andMonash Proteomics & Metabolomics Platform https://doi.org/10.82509/pymc-dr28
25_26_Round 1 Dr William Roman Monash University Genome-Scale Functional Screen to Discover Therapeutic Targets for Muscle Atrophy and Regeneration Victorian Centre for Functional Genomics (PeterMac) https://doi.org/10.82509/vtza-hb24
24_25_Round 2 A/Prof. Amee George The Australian National University Developing humanised models of Diamond Blackfan Anaemia Syndrome Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI) https://doi.org/10.82509/n2kg-df45
24_25_Round 2 Dr Ao Wen Zhuang The University of Melbourne Patient-derived iPSC airway epithelial assay systems to develop Jagged-1 inhibitors targeting the root cause of muco-obstructive lung diseases Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI) https://doi.org/10.82509/y9ct-nr90
24_25_Round 2 Dr Christian Makhoul The University of Melbourne CRISPR phenotype screen and machine learning to understand Motor Neurone Disease pathogenesis Victorian Centre for Functional Genomics (PeterMac) https://doi.org/10.82509/ntnh-1950
24_25_Round 2 Prof. Claudia Nold Hudson Institute of Medical Research Novel Immunologic Intervention for Interferon Driven Autoimmune Diseases Phenomics Australia node: Monash Organoid Program (Monash Uni)Bioplatforms Australia node: Monash Proteomics and Metabolomics Platform (Monash Uni) https://doi.org/10.82509/kjjz-9s40
24_25_Round 2 Dr Harriet Fitzgerald Hudson Institute of Medical Research Determining the role of endometrial dysfunction in endometriosis Monash Organoid Program (Monash Uni) https://doi.org/10.82509/bcm4-m109
24_25_Round 2 Prof. Leanne Dibbens University of South Australia Identifying re-purposed drugs for KCNT1 epilepsy using cell and animal models Australian Transgenic Drosophila Facility (PeterMac) https://doi.org/10.82509/crw5-pw87
24_25_Round 2 Ms Lucy Bradbury University of Queensland Development of a Primary CNS Lymphoma (PCNSL)-Brain Organoid co-culture model Australian Organoid Facility (UQ) https://doi.org/10.82509/75em-kn44
24_25_Round 2 Dr Travis Ruan Garvan Institute of Medical Research Reprogramming the Breast Cancer Microenvironment to Improve Anti-Tumour Immunity Victorian Centre for Functional Genomics (PeterMac) https://doi.org/10.82509/35cy-r397
24_25_Round 2 Dr Tan Nguyen Walter and Eliza Hall Institute/exteRNA Target identification of novel anti-cancer therapeutic Phenomics Australia node: Monash Functional Genomics Platform (Monash)Bioplatforms Australia node: Drug Target Idenfitication Platform (Monash) https://doi.org/10.82509/gsmz-x293
24_25_Round 1 Dr Aakanksha Dixit The University of Queensland Developing a humanized mouse model for Multiple Sclerosis Monash Genome Modification Platform (Monash) https://doi.org/10.82509/g06z-nz80
24_25_Round 1 Dr Alexander Maytum Murdoch Children’s Research Institute Studying enhancer function and the genetics of blood cell development from human induced pluripotent stem cells Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI) https://doi.org/10.82509/xr1v-n973
24_25_Round 1 Dr Aude Dorison Murdoch Children’s Research Institute Screening for new treatments for glomerular disease with a new stem cell reporter line Phenomics Australia node: Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI)Therapeutic Innovation Australia node: Drug Discovery Facility https://doi.org/10.82509/5952-mk69
24_25_Round 1 Dr Caitlin Finney Westmead Institute for Medical Research Testing precision medicines for Alzheimer's disease using advanced 3D human brain models Victor Chang Stem Cell Production Facility (VCCRI) https://doi.org/10.82509/y2gj-7v56
24_25_Round 1 Dr Charlene M Magtoto Walter and Eliza Hall Institute of Medical Research Creating an immunocompetent preclinical prostate cancer model to investigate targeting a tumour-driving transcription factor to stop disease Melbourne Advanced Genome Editing Centre (ONJCRI/WEHI) https://doi.org/10.82509/ev4r-k893
24_25_Round 1 Dr Denny Cottle Monash Biomedicine Discovery Institute Developing rapid Pharmacodynamic AURKA Targeted Protein Degrader screening mice Monash Genome Modification Platform (Monash) https://doi.org/10.82509/zvft-xp45
24_25_Round 1 Dr James McNamara Murdoch Children's Research Institute Developing novel models of cardiomyopathy for therapeutic testing Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI) and Melbourne Advanced Genome Editing Centre (ONJCRI/WEHI) https://doi.org/10.82509/mfzq-y642
24_25_Round 1 Dr Katharine Goodall Murdoch Children's Research Institute Gene therapy to cure primary immunodeficiencies Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI) https://doi.org/10.82509/atd5-kg38
24_25_Round 1 Dr Lachlan Jolly The University of Adelaide Overcoming Silence in Neurodevelopmental Disorder Gene Diagnosis Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility (MCRI) https://doi.org/10.82509/s8dk-a066
24_25_Round 1 Dr Lauren Elizabeth Bleakley Florey Institute of Neuroscience and Mental Health Engineering genetic mouse models of severe childhood epilepsy to test the efficacy of venom peptides as a therapeutic strategy Monash Genome Modification Platform (Monash) https://doi.org/10.82509/jx68-k477
24_25_Round 1 Dr Sara Hlavca Monash University Identifying patient-specific treatments that target plasticity in colorectal cancer via high throughput screening Victorian Centre for Functional Genomics (PeterMac) https://doi.org/10.82509/840j-5j19
23_24_Round 2 Dr Allara Zyberberg Murdoch Children’s Research Institute Developing reporter lines to enhance human kidney micro-organoids Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility https://doi.org/10.82509/5j50-5273
23_24_Round 2 Dr Andrew Bejoy Das Murdoch Children’s Research Institute High-throughput identification of targets that improve kidney organoid generation protocols Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility and Victorian Centre for Functional Genomics https://doi.org/10.82509/6xez-kr46
23_24_Round 2 Dr Chun Yuen Chow The University of Queensland A novel therapeutic intervention for genetic epilepsies using spider-venom peptides Genome Engineering and Disease Modelling Service (UQ - AIBN). https://doi.org/10.82509/tn8t-3173
23_24_Round 2 Dr Chengxue  Qin Monash University Development of Humanised Mice to Improve the Translatability for Cardiopulmonary Disease Monash Genome Modification Platform https://doi.org/10.82509/5br4-d494
23_24_Round 2 Prof. Deborah Marsh  University of Technology Sydney FDA-approved therapeutic compound library screen to discover new drugs to treat ARID1A mutant ovarian cancer ANU Centre for Therapeutic Discovery https://doi.org/10.82509/9k1d-b776
23_24_Round 2 Dr Dilys Leung Monash University Identification of personalised treatment strategies for breast cancer through high-throughput screening Victorian Centre for Functional Genomics and Monash Organoid Program https://doi.org/10.82509/ww7y-kv68
23_24_Round 2 Dr Laura Cook University of Melbourne A high throughput human organoid model to measure effects of co-cultured immune cells Victorian Centre for Functional Genomics https://doi.org/10.82509/8exm-f854
23_24_Round 2 Dr Louise Robertson The University of Adelaide Next-generation CRISPR therapeutics for autosomal dominant retinitis pigmentosa Phenomics Australia node: South Australia Genome Editing FacilityTherapeutic Innovation Australia node: Vector and Genome Engineering Facility https://doi.org/10.82509/hz3j-jw23
23_24_Round 2 Dr Natasha Kelly Tuano Murdoch Children’s Research Institute Deciphering the role of the kinome in skeletal muscle and their potential use as a therapeutic target in disease Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility and Monash Functional Genomics Platform https://doi.org/10.82509/xsr0-z276
23_24_Round 2 Dr Trent Woodruff The University of Queensland Developing new tools to enable the translation of complement therapeutics for human disease Monash Genome Modification Platform https://doi.org/10.82509/3205-bb24
23_24_Round 2 Dr Yuanzhao Cao The University of Queensland A chloride ion channel as a novel therapeutic target for ischaemic heart disease Monash Genome Modification Platform https://doi.org/10.82509/rf2y-md51
23_24_Round 1 Dr Suad Mohamed Abdirahman Peter MacCallum Cancer Centre High throughput screening to identify new therapeutic strategies for mucinous ovarian cancer patients Victorian Centre for Functional Genomics https://doi.org/10.82509/0rjn-2b18
23_24_Round 1 Dr Nicole J. Van Bergen Murdoch Children's Research Institute Development of iPSC models for ASO screening for TRAPPC4 neurodevelopmental disorder Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility https://doi.org/10.82509/52qh-h634
23_24_Round 1 Ms Rikki Brown Harry Perkins Institute Generation of Oral Carcinoma Patient-Derived Organoids for Personalised Cancer Research Perkins Cancer Biobank https://doi.org/10.82509/megh-9025
23_24_Round 1 Prof Helen Abud Monash University and Cabrini Health Personalised treatment strategies for patients with early-onset metastatic colorectal cancer Victorian Centre for Functional Genomics and Monash Functional Genomics Platform https://doi.org/10.82509/2b6r-gx60
23_24_Round 1 Dr Iva Nikolic oNKo-Innate Pty Ltd Methodology development for high-throughput compound screening of primary human immune cell cytotoxicity in 3D Victorian Centre for Functional Genomics https://doi.org/10.82509/n1xy-vk83
23_24_Round 1 Dr Remy Robert Monash University Development of human GPCR knock-in mice for assessment of therapeutic antibodies Melbourne Advanced Genome Editing Centre https://doi.org/10.82509/sfzj-8a72
23_24_Round 1 Dr Naisana Seyedasli University of Sydney & Centre for Cancer Research Establishing a targeted treatment strategy using epigenetic reprogramming against adverse EMT-induced tumour plasticity in head and neck (oral) squamous cell carcinoma Monash Genome Modification Platform https://doi.org/10.82509/9603-1820
23_24_Round 1 Dr Holly Voges Murdoch Children's Research Institute Developing a human induced pluripotent stem cell reporter line for heart valve disease modelling Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility https://doi.org/10.82509/wbza-7b96
23_24_Round 1 Dr Kevin Watt Murdoch Children's Research Institute Generation of mouse models of inherited heart failure to test the efficacy of novel stem cell based therapies Melbourne Advanced Genome Editing Centre https://doi.org/10.82509/tbn7-6d23
22_23_Round 2 Prof James Hudson QIMR Berghofer Development of an epicardial lineage tracing human pluripotent stem cell line to identify new cardiac therapeutics Induced Pluripotent Stem Cell Derivation & CRISPR Gene Editing Facility https://doi.org/10.82509/rdmn-w236
22_23_Round 2 Dr Graham A. Mackay The University of Melbourne MRGPRX2-dependent activation of mast cells: insight to novel therapeutic innovation Victorian Centre for Functional Genomics https://doi.org/10.82509/7ffy-5a63
22_23_Round 2 Dr Brett McKinnon The University of Queensland High throughput screening of micro-organoids for assessing heterogeneity and precision medicine potential in endometriosis Victorian Centre for Functional Genomics https://doi.org/10.82509/qdke-nc06
22_23_Round 2 Dr Svenja Pachernegg Murdoch Children's Research Institute Using iPSCs to determine the role of NR2F2 in ovarian development and 46,XX sex reversal Induced Pluripotent Stem Cell Derivation & CRISPR Gene EditingFacility https://doi.org/10.82509/wa1k-4q04
22_23_Round 2 Dr Ada Koo The University of Melbourne Developing transcriptomic and morphological profiling of macrophages to mine the microbiome Victorian Centre for Functional Genomics https://doi.org/10.82509/xmcn-vy05
22_23_Round 2 Dr Alexander Nicholas Combes Monash University New therapeutic strategies and targets to suppress acute kidney injury Victorian Centre for Functional Genomics and Monash Functional Genomics Platform https://doi.org/10.82509/p6pk-6q12
22_23_Round 2 Dr Simon Preston Anaxis Pharma Pty Ltd Evaluating human organoids as model systems in drug development Monash Organoid Program https://doi.org/10.82509/5vp9-4a25
22_23_Round 2 A/Prof Edwina McGlinn Monash University Tick tock, tick tock… Mechanisms pacing the Hox clock Monash Functional Genomics Platform https://doi.org/10.82509/h217-k558
22_23_Round 2 Dr Zhian Chen The University of Queensland The role of ferroptosis and oxidative stress in regulating immunity Monash Functional Genomics Platform https://doi.org/10.82509/v309-sa04
Round Lead applicant Affiliation Project title Phenomics Australia node ( Capability provider) DOI