We’re excited to share that Phenomics Australia has published a compelling commentary in Mammalian Genome Journal!
In this commentary, we explore the evolving landscape of pre-clinical research models, highlighting the growing role of non-animal technologies (NATs) in biomedical innovation.
While the rise of NATs—including in silico, cell-free, organ-on-chip, and in vitro systems such as organoids—has stimulated expectations about reducing animal use in research, their true potential lies in complementing rather than replacing traditional models. With in vitro techniques gaining widespread adoption and national investment in Australia, this paper emphasises the need for a balanced and informed approach that leverages the strengths of both animal and non-animal systems to enhance the effectiveness and translational value of therapeutic development.
Acknowledgments: The authors acknowledge the expertise of all the scientists, staff, students, and technicians at the 11 Australian research organisations that partner to constitute Phenomics Australia, responsible for the development and delivery of research infrastructure capabilities. The authors acknowledge the Phenomics Australia Executive and Directors for their guidance in preparation of this manuscript. The authors also acknowledge long-term and sustained funding from the Australian Government through the National Collaborative Research Infrastructure Strategy (NCRIS) program that enables Phenomics Australia, as well as the ongoing collaborations with other NCRIS-enabled national research infrastructure providers and international partners, especially through membership of the International Mouse Phenotyping Consortium.
Read the full article here:
